import pandas as pd
# Example DataFrame
df = pd.DataFrame.from_dict({'Name' : ['May21', 'James', 'Adi22', 'Hello', 'Girl90'],
'Volume': [23, 12, 11, 34, 56],
'Value' : [21321, 12311, 4435, 32454, 654654]})
df['Name'] = df['Name'].str.replace('\d+', '')
print(df)